Outcomes Working Group

Chair / Co-Chairs: Christina Jern, Arne Lindgren, and Jane Maguire

The ISGC Genetics of Stroke Functional Outcome (GISCOME) network, is led by Prof Christina Jern, Prof Arne Lindgren and Prof Jane Maguire. The aim of this network is to investigate the genetic influences on stroke outcomes, especially functional ability. In phase 1, the GISCOME investigators established the world’s first genome wide association (GWA) genetic dataset for functional outcome after overall ischemic stroke, and reported the first GWAs significant variant for this phenotype. Phase-2 is now underway and has now identified over 8000 retrospective cases with the aim to meta-analyse and replicate this result. This is an ongoing collaboration and all are welcome to join this group.